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Carol A Lange Selected Research

Progesterone Receptors (Progesterone Receptor)

12/2021Stress sensing within the breast tumor microenvironment: how glucocorticoid receptors live in the moment.
1/2021Progesterone Receptors Promote Quiescence and Ovarian Cancer Cell Phenotypes via DREAM in p53-Mutant Fallopian Tube Models.
1/2021Progesterone promotes immunomodulation and tumor development in the murine mammary gland.
1/2021Insulin receptor substrate-1 (IRS-1) mediates progesterone receptor-driven stemness and endocrine resistance in oestrogen receptor+ breast cancer.
1/2019Phosphorylated Progesterone Receptor Isoforms Mediate Opposing Stem Cell and Proliferative Breast Cancer Cell Fates.
1/2018Progesterone receptors (PR) mediate STAT actions: PR and prolactin receptor signaling crosstalk in breast cancer models.
1/2017Posttranslationally modified progesterone receptors direct ligand-specific expression of breast cancer stem cell-associated gene programs.
2/2016Active FOXO1 Is a Key Determinant of Isoform-Specific Progesterone Receptor Transactivation and Senescence Programming.
1/2016Tumour and cellular distribution of activated forms of PR in breast cancers: a novel immunohistochemical analysis of a large clinical cohort.
1/2016Modifications to glucocorticoid and progesterone receptors alter cell fate in breast cancer.
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Carol A Lange Research Topics

Disease

60Breast Neoplasms (Breast Cancer)
12/2021 - 01/2003
43Neoplasms (Cancer)
12/2021 - 01/2003
5Ovarian Neoplasms (Ovarian Cancer)
01/2021 - 08/2010
5Triple Negative Breast Neoplasms
01/2020 - 09/2013
5Neoplasm Metastasis (Metastasis)
01/2018 - 01/2010
5Carcinogenesis
01/2016 - 12/2008
3Hypersensitivity (Allergy)
01/2021 - 06/2003
3Hypoxia (Hypoxemia)
11/2018 - 09/2013
1Disease Progression
12/2018
1Leukemia
06/2012
1Retinoblastoma (Glioblastoma, Retinal)
08/2011

Drug/Important Bio-Agent (IBA)

33Progesterone Receptors (Progesterone Receptor)IBA
12/2021 - 01/2003
20Hormones (Hormone)IBA
12/2021 - 01/2003
17Progestins (Progestagens)IBA
01/2017 - 12/2004
16SteroidsIBA
12/2021 - 01/2003
16ProgesteroneFDA LinkGeneric
01/2021 - 01/2008
15Phosphotransferases (Kinase)IBA
01/2021 - 01/2005
12LigandsIBA
12/2021 - 12/2004
11Estrogen ReceptorsIBA
12/2021 - 01/2008
11Phenobarbital (Luminal)FDA Link
01/2021 - 08/2011
8Steroid Receptors (Steroid Receptor)IBA
01/2020 - 02/2004
8Intercellular Signaling Peptides and Proteins (Growth Factors)IBA
01/2017 - 01/2003
8Proteins (Proteins, Gene)FDA Link
11/2016 - 01/2005
7Protein-Tyrosine Kinases (Tyrosine Kinase)IBA
01/2021 - 01/2005
7Protein Kinases (Protein Kinase)IBA
01/2018 - 12/2007
7Estrogens (Estrogen)FDA Link
01/2018 - 03/2008
6Protein Isoforms (Isoforms)IBA
01/2019 - 05/2011
6Epidermal Growth Factor (EGF)IBA
01/2017 - 01/2005
5Glucocorticoid Receptors (Glucocorticoid Receptor)IBA
12/2021 - 01/2016
4p38 Mitogen-Activated Protein KinasesIBA
01/2020 - 05/2007
4Messenger RNA (mRNA)IBA
03/2016 - 08/2012
4Transcription Factors (Transcription Factor)IBA
04/2014 - 05/2005
4Mitogen-Activated Protein KinasesIBA
01/2007 - 01/2003
3Estrogen Receptor Modulators (Antiestrogen)IBA
12/2018 - 06/2012
3MitogensIBA
01/2018 - 03/2008
3Peptides (Polypeptides)IBA
04/2012 - 12/2007
3Hepatocyte Growth Factor (Growth Factor, Hepatocyte)IBA
04/2012 - 01/2010
3EnzymesIBA
12/2008 - 03/2008
2Androgen Receptors (Androgen Receptor)IBA
12/2021 - 01/2007
2human ERBB2 proteinIBA
12/2021 - 01/2017
2Paclitaxel (Taxol)FDA LinkGeneric
01/2021 - 11/2018
2TamoxifenFDA LinkGeneric
01/2021 - 01/2021
2Aryl Hydrocarbon Receptors (Aryl Hydrocarbon Receptor)IBA
01/2021 - 11/2018
2AgarIBA
01/2020 - 06/2011
2Indicators and Reagents (Reagents)IBA
01/2019 - 01/2005
2Biomarkers (Surrogate Marker)IBA
01/2019 - 01/2017
2Biological ProductsIBA
11/2018 - 01/2016
2Estrogen Receptor alphaIBA
01/2018 - 04/2014
2Small Interfering RNA (siRNA)IBA
01/2017 - 05/2007
2Thromboplastin (Tissue Factor)IBA
02/2015 - 06/2010
2Cyclin D1IBA
04/2014 - 08/2011
2Cytoplasmic and Nuclear Receptors (Nuclear Receptors)IBA
02/2014 - 05/2011
2Histone MethyltransferasesIBA
06/2012 - 12/2008
2ErbB Receptors (EGF Receptor)IBA
05/2007 - 01/2007
1Mineralocorticoid Receptors (Mineralocorticoid Receptor)IBA
12/2021
1Insulin (Novolin)FDA Link
01/2021
1Insulin Receptor Substrate ProteinsIBA
01/2021
1Progesterone CongenersIBA
01/2021
1RNA (Ribonucleic Acid)IBA
01/2021
1human PELP1 proteinIBA
01/2018
1Prolactin Receptors (Prolactin Receptor)IBA
01/2018
1ClaudinsIBA
01/2018
1Aurora Kinase AIBA
01/2018
1Notch ReceptorsIBA
01/2018
1Glutathione (Reduced Glutathione)IBA
09/2017
1purineIBA
09/2017
1Calcitriol Receptors (Calcitriol Receptor)IBA
09/2017
1Biological FactorsIBA
01/2017
1Mifepristone (RU 486)FDA Link
01/2017
1Complement System Proteins (Complement)IBA
01/2017
1PromegestoneIBA
01/2017
1aglepristoneIBA
01/2017
1onapristoneIBA
01/2017
1Serine (L-Serine)FDA Link
03/2016
1Dexamethasone (Maxidex)FDA LinkGeneric
03/2016
1Hydrocortisone (Cortisol)FDA LinkGeneric
03/2016
1GlucocorticoidsIBA
01/2016
1progesterone receptor BIBA
10/2013
1Glucose (Dextrose)FDA LinkGeneric
09/2013
1Reactive Oxygen Species (Oxygen Radicals)IBA
09/2013
1Peptide Hydrolases (Proteases)FDA Link
08/2012
1Carrier Proteins (Binding Protein)IBA
06/2012
1Nucleosomes (Nucleosome)IBA
06/2012
1Mitogen-Activated Protein Kinase Kinases (MEKs)IBA
06/2012
1Cyclic AMP Response Element-Binding Protein (Cyclic AMP-Responsive DNA-Binding Protein)IBA
06/2012
1N- phenylacetoaminomethylene- DL- p- nitrophenylalanine (A 101)IBA
04/2012
1tyrosine receptor (receptor, tyrosine)IBA
04/2012
1Receptor Protein-Tyrosine Kinases (Tyrosine Kinase Receptors)IBA
09/2011
1Cytostatic AgentsIBA
08/2011
1Estradiol (Delestrogen)FDA LinkGeneric
05/2011
1RNA IsoformsIBA
08/2010
1Adenosine Monophosphate (AMP)IBA
08/2010
12-MethoxyestradiolIBA
06/2010
1STAT5 Transcription FactorIBA
06/2010
1macrophage stimulating proteinIBA
01/2010
1Mitogen-Activated Protein Kinase 7IBA
01/2010

Therapy/Procedure

17Therapeutics
01/2021 - 01/2008
4Hormone Replacement Therapy (Therapy, Hormone Replacement)
04/2014 - 09/2009
2Drug Therapy (Chemotherapy)
01/2021 - 11/2018
1Immunomodulation
01/2021